简单介绍：Recombinant Human Interferon gamma produced in E. coli is a single, non-glycosylated, polypeptide chain containing 144 amino acids and having a molecular mass of 16879 Dalton.
The major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon ａnd its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly by T-cells ａnd natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 ａnd CD8. The synthesis of IFN-gamma is induced, among other things, by Interleukin-2, FGF-basic, ａnd EGF.
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