产品名称 骨成型蛋白受体1A抗体
产品缩写 BMPR1A
蛋 白 名 Bone morphogenetic protein receptor type-1A
别 称 ALK3; SKR5; CD292; ACVRLK3
来 源 小鼠
特 异 性 抗人,小鼠
分 子 量 60kDa
克隆类型 单克隆抗体：IgG1；克隆号：4B7B2
应 用 IH(P)免疫组化(石蜡)；IC细胞免疫化学；WB免疫印迹；FC流式细胞检测；ELISA
成 分 Ascitic fluid containing 0.03% sodium azide.
免 疫 原 Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.
保存条件 连续使用时4°C存储，保质期六个月；长期存储时建议分装为10ul以上小包装-20°C存储，并避免反复冻融，保质期一年。
背景资料 The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A ａnd BMPR1B ａnd the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 ａnd ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas ａnd activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD ａnd type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
