Angiostatin is a ~30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Recombinant angiostatin is expressed in Pichia, GS115.
Activity: The activity is assayed on anti-proliferation and anti-migration of endothelial cells in vitro and anti-angiogenesis in vivo.
Purity: 98% by HPLC.
M.W.: 30845
Ref.: O’Reilly, M. S., et al. 1994. Cell 79, 315-328
我们是北京普罗吉生物科技发展有限公司。我公司现有38种重组蛋白和14种抗体，并且产品目录还以极快的速度增加中。目前我们可以根据客户需求制备几毫克至几千克的重组蛋白或抗体。此外，我公司还可依照客户需求提供蛋白表达、纯化及复性服务。
依托于普罗吉公司在大规模制备重组蛋白和抗体方面的国际先进技术，我们正广泛寻求合作伙伴，为之提供高品质低价格的产品，以实现共同繁荣发展的目标。我们坚信我们所提供的服务一定可以使您更有效的控制生产成本。
目前我们正提供高品质的重组人组织因子（rh-TF）、成纤维细胞生长因子（bFGF）、白血病抑制因子（LIF）、血小板衍生因子（PDGF-BB）、超氧化物歧化酶（SOD）和血管内皮生长因子165（VEGF-165）等，经活性、纯度检测均达到或超过目前国际同类产品标准。我们所制备的重组蛋白均可达到95%以上的纯度，部分产品可达到99%以上的纯度。
Proteins:
Angiostatin, Arginine Deiminase, Basic Fibroblast Growth Factor, Ciliary Neurotrophic Factor, Endostatin, Endostatin, His-Tag, Endostatin Mutant C33AC173A, Endostatin Mutant C135AC165A, Endostatin Mutant all-Ala, GroEL (D87K), Glial Cell Line-Derived Neurotrophic Factor, Heat Shock Protein 90β, Heat Shock Protein 90β Fragment 2, Interleukin-6, N-Terminal Fragment of Kinesin Heavy Chain, C-Terminal Fragment of Kinesin Heavy Chain, Leukemia Inhibitory Factor, Luciferase, Myoglobin, Apo-Myoglobin, Nucleolin, C-Fragment of Nucleolin, β-Nerve Growth Factor, C-Fragment of Nonmuscle Myosin Heavy Chain 9, Protein Disulfide Isomerase, PEX, Stromal Cell-Derived Factor 1α, Sup35 (NM), Superoxide Dismutase, Tissue Factor, Tumor Necrosis Factor-α, Vascular Endothelial Growth Factor 165, Voltage Dependent Anion Channel-1
Antibodies:
Anti-Angiostatin, Anti-Arginine Deiminase, Anti-Ciliary Neurotrophic Factor, Anti-CXCR4, Anti-Endostatin, Anti-Fibrinogen, Anti-Gro EL (D87K), Anti-Heat Shock Protein 90β, Anti-Nucleolin, Anti-C-Fragment of Nucleolin, Anti-Nonmuscle Myosin Heavy Chain 9, Anti-PEX, Anti-Soluble Tissue Factor, Anti-Voltage Dependent Anion Channel-1
