N-Terminal Fragment of Kinesin Heavy Chain, His-Tagged, Human, Recombinant (rh-nKHC) |
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The kinesin family of motor proteins comprises at least two forms of conventional kinesin, and they are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains of approximately 120 kDa and two light chains of approximately 65 kDa. Kinesin motor activity is dependent on the presence of ATP and microtubules. rh-nKHC is a N-terminal fragment of uKHC with a histidine-tagged expressed in E. coli.
Purity: ≥ 95% by SDS-PAGE.
M.W.: 30192
Ref.: Navone, F., et al. 1992. J. Cell Biol. 117, 1263-1275
Niclas, J., et al. 1994. Neuron 12, 1059-1072
C-Terminal Fragment of Kinesin Heavy Chain, His-Tagged, Human, Recombinant (rh-cKHC) |
|
The kinesin family of motor proteins comprise at least two forms of conventional kinesin, and they are encoded by different genes and designated as ubiquitous kinesin, which is expressed in all cells and tissues, and neuronal kinesin, which is expressed exclusively in neuronal cells. While the kinesin heavy chain contains motor activity, evidence suggests that the kinesin light chain is involved in either modulation of kinesin heavy chain activity or in cargo binding. The motor protein kinesin is a heterotetramer composed of two heavy chains of approximately 120 kDa and two light chains of approximately 65 kDa. Kinesin motor activity is dependent on the presence of ATP and microtubules. rh-cKHC is a C-terminal fragment of uKHC with a histidine-tagged expressed in E. coli.
Purity: ≥ 95% by SDS-PAGE.
M.W.: 22784
Ref.: Navone, F., et al. 1992. J. Cell Biol. 117, 1263-1275
Niclas J., et al. 1994. Neuron 12, 1059-1072
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