艾美捷LKT Labs-双叶碱解决方案

艾美捷LKT Labs-双叶碱#B3211参数说明： 

Cas No.：485-49-4

纯度：≥98%

公式：C₂₀H₁₇NO₆

配方重量：367.35

化学名称：6R-6-甲基-5，6-二氢-7H-[8，5]二氧杂环戊二烯并[1，3-g]异喹啉-4-基]-5H-呋喃[5，6-g][3，4]苯并二氧杂环戊烯-1-酮

IUPAC名称：6R-6-甲基-5，6-二氢-7H-[8，5]二氧戊二醇[1， 3-g]异喹啉-4-基]-5H-呋喃[5，6-g][3，4]苯并二氧杂环戊烯-1-酮

同义词：d-二葫芦碱

外观：白色至类白色粉末

LKT Labs-双叶碱文献引用：

Dela Peña IJ, Lee HL, Yoon SY, et al. The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABA(A) receptor in human neuroblastoma cells ａnd exhibited anxiolytic-like effects in mice. Drug Discov Ther. 2013 Feb;7(1):18-23. PMID: 23524939.

Torkaman-Boutorabi A, Soltani S, Oryan S, et al. Involvement of the dorsal hippocampal GABA-A receptors in histamine-induced facilitation of memory in the Morris water maze. Pharmacol Biochem Behav. 2013 Apr;105:142-50. PMID: 23438692.

Ionov ID, Roslavtseva LA. Coadministration of bicuculline ａnd NMDA induces paraplegia in the rat. Brain Res. 2012 Apr 27;1451:27-33. PMID: 22445063

Ji G, Neugebauer V. Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 ａnd GABA(A) receptors. J Neurophysiol. 2011 Nov;106(5):2642-52. PMID: 21880942.

Costa LG, Doctor SV, Murphy SD. Antinociceptive ａnd hypothermic effects of trimethyltin. Life Sci. 1982 Sep 13;31(11):1093-102. PMID: 6890611.

Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization ａnd prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline ａnd penicillin. Brain Res. 1982 Jan 28;232(1):41-56. PMID: 7055710.

LKT Laboratories（LKT Labs）注于防癌抗癌特殊化学品研究和开发域。主要包括：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成等。同时注研究用小分子的合成，纯化和分离。主要应用于癌症和神经科学等，包括蛋白激酶抑制剂、离子通道调节剂和激活剂等。艾美捷科技是LKT Labs的中国代理商，为科研工作者提供优质的产品与服务。

来源：https://www.amyjet.com/news/LKT-Laboratories-new.shtml