中英文说明丨艾美捷 S-乙酰基-L-谷胱甘肽

Product Info

Cas No. 3054-47-5

Purity ≥98%

Formula C12H19N3O7S

Formula Wt. 349.36

Chemical Name

5-[[3-acetylsulfanyl-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-2-amino-5-oxopentanoic acid

IUPAC Name γ-Glutamyl-S-acetylcysteinylglycine

Synonym L-glutathione, S-acetyl

Melting Point 199-204°C (dec.)

Solubility Soluble in hot water. Practically insoluble in cold water.

Appearance White Powder

艾美捷 LKT Labs S-乙酰基-L-谷胱甘肽是一种谷胱甘肽衍生物，可以增加细胞内谷胱甘肽，类似于药。它可用于补充HIV感染期间发生的还原型谷胱甘肽的消耗，并抑制HIV复制。然而，发现它通过消耗细胞内谷胱甘肽水平而不是增加它来选择性地诱导人淋巴瘤细胞，Daudi，Raji和Jurkat细胞的凋亡。

S-乙酰基-L-谷胱甘肽基础信息：

编号：A1016

cas：3054-47-5

纯度：≥98%

公式：C12H19N3O7S

配方重量：349.36

化学名称：5-[[3-乙酰硫基-1-羧甲基氨基-1-氧代丙烷-2-基]氨基]-2-氨基-5-氧代戊酸

IUPAC名称：γ-谷氨酰-S-乙酰半胱氨酸甘氨酸

同义词：L-谷胱甘肽， S-乙酰基

熔点：199-204°C （十进制）

溶解度：溶于热水。几乎不溶于冷水。

外观：白色粉末

S-乙酰基-L-谷胱甘肽文献参考：

Fraternale A1, Paoletti MF, Casabianca A, et.al. Inhibition of murine AIDS by pro-glutathione (GSH) molecules. Antiviral Res. 2008 Feb;77(2):120-7. PMID: 18164447

Locigno R1, Pincemail J, Henno A, et.al. S-acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH-independent mechanism. Int J Oncol. 2002 Jan;20(1):69-75. PMID: 11743644

Galzigna L1, Rizzoli V, Schiappelli P et.al. S-acetyl- ａnd S-phenylacetyl-glutathione as glutathione precursors in rat plasma ａnd tissue preparations. Enzyme Protein. 1994-1995;48(2):98-104. PMID: 7581748

来源：https://www.amyjet.com/products/LKT-A1016-1g.shtml