Milligard® filters provide the finest prefiltration available. Milligard filters are constructed of homogeneous polymers of cellulose esters on a polyester web resulting in a versatile filter with high reproducibility and efficacy due to the highly retentive, non-fiber releasing membrane. The homogenous cellulose ester membrane provides the high retention needed during critical prefiltration steps while protecting more expensive downstream filtration devices from premature plugging.
Milligard filters are available in single and double layer formats, as well as a special low protein binding version constructed of low protein binding cellulose esters that is designed for the removal of particles and microorganisms in applications where maximizing protein recovery is critical.
Regulatory Compliance
Milligard filters are designed, developed, and manufactured in accordance with a Quality Management System approved by an accredited registering body to an ISO® 9000 Quality Systems Standard and are shipped with a Certificate of Quality. Each Opticap™ XL and XLT capsule and cartridge filter is supported by a Validation Guide for compliance with regulatory requirements.
For traceability and easy identification, each filter is marked with identifying characteristics.
Multiple Formats Available
Milligard filters and Milligard Low Protein Binding (LPB) filters are available in single or double layer, three formats, many pore sizes, and multiple configurations that vary by filtration area and the type of inlet/outlet connection.
- OptiScale™ small scale disposable capsule filters
- Opticap XL and XLT disposable capsule filters
- Cartridge filters
Applications
Cell Culture Media
Effectively remove particles and colloidal contaminants without obstructing the flow of vital media constituents. Milligard prefilters provide the high flow rates and consistently high throughput required to accomplish the separation in a timely and cost-effective manner.
Final Aseptic Fill of Small Volume Parenterals (SVP)
Extend the service life of downstream sterilizing filters by removing colloidal and particulate contaminants.
Large Volume Parenterals (LVP)
Extend the service life of downstream sterilizing filters by removing colloidal and particulate contaminants. Extremely robust and able to withstand high operating pressures, Milligard filters offer dependable retention and high flow rates needed for high volume manufacturing.
Plasma Proteins—Human Albumin
Remove colloids, aggregated and non-product proteins, lipids and particles prior to downstream purification without retaining the fractions of interest. Milligard filters provide superior protection of downstream sterile filters and/or chromatography columns.
Serum
Effectively remove lipids, colloids, and particles from serum before the final sterilizing filtration without obstructing the passage of serum proteins. Milligard filters provide high flow rates and consistently high throughput.
OptiScale Process Development Screening Tool
OptiScale disposable capsule filters provide a convenient small volume option for process screening and scaling. These "drop in" filters are ideal for evaluating biopharmaceuticals. OptiScale capsule filters offer speed-to-market strategies for efficiently developing compounds and biotherapeutics.
The OptiScale disposable capsule is ideally suited for process development and screening. OptiScale capsules are faster and easier to set-up than conventional 47 mm discs.
Opticap XL and XLT Disposable Capsule Filters
Opticap XL and XLT capsule filters eliminate the time and expense associated with assembling, cleaning, and validating stainless steel housings. The capsule patented design allows unparalleled thermal and hydraulic stress resistance, resulting in reliability, high confidence in the sterility process and improved cleanliness. The unique capsule design with pleated Milligard membrane minimizes hold-up volume and reduces production losses.
Opticap XL 2, 4, 5 and 10 capsule filters with Milligard media are available in multiple filtration areas, providing an optimal choice for every application.
Opticap XLT 10, 20 and 30 T-line Capsule Filters with Milligard media are available with or without a pressure gauge port for ease in monitoring process conditions. The T-line design accommodates series or parallel filtration to match your application needs, and a specially-designed stand enables quick and easy integration of the Opticap XLT into your existing process.
Cartridge Filters
Milligard cartridge filters provide high throughput with minimal differential pressure. Cartridges are robust, strong, resilient and are designed to withstand multiple steam-in-place cycles. Milligard cartridge filters are integrity tested during the manufacturing process.
A full range of filtration areas is available to suit varying application requirements. A variety of connection options are offered for easy adaptation to existing housings.
上海微滤净化技术有限公司净化技术包括微孔过滤技术、超滤(错流)技术,纳米过滤技术以及反渗透技术,同时作为全球电子行业最著名过滤器公司Mykrolis(Millipore) 华东地区总代理,本着为客户提供”全流程过滤解决方案”的服务理念,专业从事于过滤及分离技术,开发和优化满足客户需要的各种过滤系统。工程及应用人员仔细考虑应用需求,选择合理的设计、工艺参数、组件及自动化程度,定向为用户提供高质量、长寿命和性能可靠的产品,以最大限度地降低用户的使用成本。我们提供各类液体及气体过滤系统及器材。