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Product Name | Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region |
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Antibody Type | Primary Antibodies |
Immunogen | The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | WB |
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
Species Reactivity | BovineDogGoatHorseHumanMouseRabbitRatZebra Fish |
Concentration | 1 mg/ml |
Purification | Affinity purified |
Gene Symbol | PPARGC1A |
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Gene Synonyms | Hide |
Gene Full Name | Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
Gene Summary | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. Hide |
Alternative Names | Hide |
Molecular Weight(MW) | 91kDa |
Sequence | 798 amino acids |
Entrez Gene | 10891 |
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SwissProt ID | Q9UBK2 |
Protein Accession | NP_037393 |
Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
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Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
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