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您的位置:首页 > 技术文献 > 产品说明 > Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region

标题Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/8/14   阅读次数:27次 >>进入该公司展台
  

Product Profile

Product Name Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Immunogen
The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WB

 
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineDogGoatHorseHumanMouseRabbitRatZebra Fish

Concentration 1 mg/ml
Purification Affinity purified


Target Information

Gene Symbol PPARGC1A
Gene Synonyms
LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
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Gene Full Name Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Gene Summary
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
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Alternative Names
LEM6
PGC-1(alpha)
PGC-1v
PGC1
PGC1A
PPARGC1
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Molecular Weight(MW) 91kDa
Sequence 798 amino acids

Database Links

Entrez Gene 10891
SwissProt ID Q9UBK2
Protein Accession NP_037393

Application

Application Notes
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.


Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

关键词:稳定性强  特异性强    灵敏度高  

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