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| Product Name | Anti-PGC1 alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1 mg/ml |
| Purification | Protein A |
| Gene Symbol | PPARGC1A |
|---|---|
| Gene Synonyms | Hide |
| Gene Full Name | PPARG coactivator 1 alpha |
| Gene Summary | The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity. [provided by RefSeq, Jul 2008] Hide |
| Molecular Weight(MW) | 91 kDa |
| Source | Rabbit |
| Cellular Localization | Cylasm. Nucleus; Nucleus ａnd Nucleus. Nucleus; PML body |
Western blot analysis using PGC1 antibody against Hep PC-12 (1) cell lysate.
Immunohistochemical analysis of paraffin-em
Immunofluorescence analysis of Hela cells using PGC1 alpha antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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