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| Product Name | Anti-CHOP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1 mg/ml |
| Purification | Protein A |
| Gene Symbol | DDIT3 |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | DNA damage inducible transcript 3 |
| Gene Summary | This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP ａnd LAP (liver activator protein), ａnd preventing their DNA binding activity. The protein is implicated in adipogenesis ａnd erythropoiesis, is activated by endoplasmic reticulum stress, ａnd promotes apoptosis. Fusion of this gene ａnd FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010] More |
| Molecular Weight(MW) | 19 kDa |
| Source | Rabbit |
| Cellular Localization | Cylasm;Nucleus |
Western blot analysis using CHOP antibody against P19 (1) cell lysate.
Immunohistochemical analysis of paraffin-em
Immunofluorescence analysis of Hela cells using CHOP antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:1000 ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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