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您的位置:首页 > 技术文献 > 产品说明 > GADD153 antibody

标题GADD153 antibody

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/8/15   阅读次数:11次 >>进入该公司展台
  

Product Profile

Product Name GADD153 antibody
Antibody Type Primary Antibodies
Product description
Rabbit Polyclonal antibody to GADD153 (DNA-damage-inducible transcript 3)This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq]
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Immunogen
Full length human GADD153 Recombinant protein.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC-PWBIHC-R

 
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity

HumanMouse

Predicted Reactivity Rat, Pig, Rhesus Monkey, BovineRat (90%), Pig (95%), Rhesus Monkey (98%), Bovine (92%)
Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
CEBPZ antibody
CHOP antibody
CHOP-10 antibody
CHOP10 antibody
GADD153 antibody
MGC4154 antibody
DDIT3 antibody
DNA damage-inducible transcript 3 protein antibody
growth arrest and DNA damage-inducible protein GADD153 antibody
c/EBP-homologous prot
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Molecular Weight(MW) 19 kDa (note) (6)
Cellular Localization Nucleus

Application

  • Application

    Sample (30 µg of whole cell lysate) A: HeLa (control) B: HeLa treated with tunicamycin (4ug/ml) 12% SDS PAGE diluted at 1:500 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Positive Control HeLa treat tunicamycin (4ug/ml)
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher. :

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

关键词:稳定性强  特异性强    灵敏度高  

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