您好，欢迎来到易推广！请登录免费注册

手机版

频道

通用机械电子元器件行业设备五金工具电工电气仪器仪表安防监控专用汽车照明灯具化工原料涂料塑胶建筑原料皮革冶金

阅读排行榜

手写达人

猜您喜欢

推荐阅读

您的位置：首页 > 技术文献 > 产品说明 > PGC1 alpha+beta [JF09-71] Catalog Number：OM637821

标题PGC1 alpha+beta [JF09-71] Catalog Number：OM637821

提供者：上海笃玛生物科技有限公司发布时间：2024/8/16 阅读次数：20次 >>进入该公司展台

Product Profile

Product Name	PGC1 alpha+beta [JF09-71]
Antibody Type	Primary Antibodies
Product description	Transcription factors exert their effects by associating with co-activator or corepressor proteins. The co-activator complexes are thought to be constitutively active, requiring only proper positioning in the genome to initiate transcription. Co-activators include the steroid receptor coactivator (SRC) ａnd CREB binding protein (CBP) families that contain histone acetyltransferase (HAT) activity, which modifies chromatin structure. PPARgamma co-activator-1 (PGC-1) is a transcriptional cofactor of nuclear respiratory factor-1 (NRF-1), PPARbeta, PPARalpha ａnd other nuclear receptors that is induced by exposure to cold temperatures ａnd is involved in regulating thermogenic gene expression, protein uncoupling, ａnd mitochondrial biogenesis. PGC-1 has a low inherent transcriptional activity when it is not bound to a transcription factor. Docking of PGC-1 to PPARgamma stimulates an apparent conformational change that then enables PGC-1 to bind to ａnd assemble into complexes, which include the additional cofactors SRC-1 ａnd CBP/p300, ａnd results in a large increase in transcriptional activity. Hide
Immunogen	recombinant protein

Key Feature

Clonality	Monoclonal
Isotype	IgG
Host Species	Recombinant rabbit
Tested Applications	WB
	WB:1:1,000
Species Reactivity	HumanMouseRat
Concentration	1 mg/mL.

Target Information

Alternative Names	LEM6 antibody Ligand effect modulator 6 antibody PERC antibody Peroxisome proliferative activated receptor gamma coactivator 1 alpha antibody Peroxisome proliferative activated receptor gamma coactivator 1 antibody Peroxisome proliferator activated receptor gamma coactivator 1 alpha antibody peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody Peroxisome proliferator-activated receptor gamma coactivator 1-alpha antibody Peroxisome proliferator-activated receptor gamma coactivator 1-beta antibody peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody PGC 1 (alpha) antibody PGC 1 alpha antibody PGC 1v antibody PGC-1(beta) antibody PGC-1-alpha antibody PGC-1-beta antibody PGC-1-related estrogen receptor alpha coactivator antibody PGC1 antibody PGC1(alpha) antibody PGC1A antibody PGC1v antibody PPAR gamma coactivator 1 alpha antibody PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6 antibody PPAR gamma coactivator 1 antibody PPAR gamma coactivator variant form antibody PPAR gamma coactivator-1beta antibody PPAR-gamma coactivator 1-alpha antibody PPAR-gamma coactivator 1-beta antibody PPARGC 1 alpha antibody PPARGC-1-alpha antibody PPARGC-1-beta antibody PPARGC1 antibody PPARGC1A antibody Ppargc1b antibody PRGC1_HUMAN antibody PRGC2_HUMAN antibody Hide
Molecular Weight(MW)	113 kDa
Cellular Localization	Nucleus.

Database Links

SwissProt ID	Q86YN6 Q9UBK2 415302 O70343 Q8VHJ7 Q811R2 Q9QYK2

Application

Application

Fig1: Western blot analysis of PGC1 alpha+beta on different lysates using anti-PGC1 alpha+beta antibody at 1/1,000 dilution. Positive control: Lane 1: Mouse brain Lane 2: Mouse heart Lane 3: Mouse kidney

Positive Control	Mouse heart tissue, mouse kidney tissue, mouse brain tissue.
Application Notes	WB:1:1,000

Additional Information

Form	Liquid
Storage Instructions	Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

关键词：稳定性强特异性强灵敏度高

上一篇：贝利励磁模块PHBDOT1000S100 2024已新在途下一篇：贝利励磁模块PHBDOT12010000 2024已新在途

相关文章

该提供者的其它文献

版权声明

① 凡本网注明"来源：易推广"的所有作品，版权均属于易推广，未经本网授权不得转载、摘编或利用其它方式使用。已获本网授权的作品，应在授权范围内

使用，并注明"来源：易推广"。违者本网将追究相关法律责任。

② 本信息由注册会员：上海笃玛生物科技有限公司发布并且负责版权等法律责任。

最新产品 - 今日最热门报道-分类浏览 - 每日产品

易推广客服微信