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您的位置：首页 > 技术文献 > 产品说明 > PGC1 alpha antibody Catalog Number：OM268255

标题PGC1 alpha antibody Catalog Number：OM268255

提供者：上海笃玛生物科技有限公司发布时间：2024/8/16 阅读次数：17次 >>进入该公司展台

Product Profile

Product Name	PGC1 alpha antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to PGC1 alphaThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity. [provided by RefSeq, Jul 2008] More
Immunogen	PPARGC1A antibody was raised against a 17 amino acid peptide near the amino terminus of human PPARGC1A.

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ELISAICC/IFIHC-PWB
	WB:1:500~1:1000 IP:1:100~1:500 IF:1:100~1:500
Species Reactivity	HumanRat
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Target Information

Gene Synonyms	PGC1A PPARGC1A LEM6 PGC1 PPARGC1 PGC-1(alpha) PGC-1v peroxisome proliferator-activated receptor gamma coactivator 1 alpha Hide
Target	PGC1 alpha
Tissue Specificity	PPARGC1A antibody is human ａnd rat reactive. At least three isoforms of PPARGC1A are known to exist; this antibody will detect all three isoforms.

Application

Application

Western blot analysis of PPARGC1A in human heart tissue lysate with PPARGC1A antibody at 1 ug/ml in (A) the absence ａnd (B) the presence of blocking peptide.
Application

Immunohistochemistry of PPARGC1A in rat heart tissue with PPARGC1A antibody at 5 ug/mL.
Application

Immunofluorescence of PPARGC1A in rat heart tissue with PPARGC1A antibody at 20 ug/mL.

Application Notes	WB:1:500~1:1000 IP:1:100~1:500 IF:1:100~1:500

Additional Information

Form	Liquid
Storage Instructions	Be stored at 4oC for three months ａnd -20oC, stable for up to one year.
Storage Buffer	PBS containing 0.02% sodium azide.

关键词：稳定性强特异性强灵敏度高

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