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| Product Name | Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFWB |
| IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | BovineDogGoatHorseHumanMousePigRabbitRat |
| Concentration | 1 mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PPARGC1A |
|---|---|
| Gene Synonyms | Hide |
| Gene Full Name | Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| Gene Summary | PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity.The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, ａnd regulate the activities of, cAMP response element binding protein (CREB) ａnd nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli ａnd the regulation of mitochondrial biogenesis, ａnd is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, ａnd the development of obesity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. Hide |
| Alternative Names | Hide |
| Molecular Weight(MW) | 91kDa |
| Sequence | 798 amino acids |
| Entrez Gene | 10891 |
|---|---|
| SwissProt ID | Q9UBK2 |
| Protein Accession | NP_037393 |
Mouse retina
Primary Antibody Dilution :
1:200
Secondary Antibody :
Donkey anti rabbit-Cy3
Secondary Antibody Dilution :
1:1000
Color/Signal Desc
Red: PPARGC1A
Gene Name :
PPARGC1A
Submitted by :
Dr. Joshua Sanes
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
| Application Notes | IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot ａnd store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
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