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您的位置：首页 > 技术文献 > 产品说明 > Caspase 3 (cleaved Asp175) antibody OM243294

标题Caspase 3 (cleaved Asp175) antibody OM243294

提供者：上海笃玛生物科技有限公司发布时间：2024/8/16 阅读次数：21次 >>进入该公司展台

Product Profile

Product Name	Caspase 3 (cleaved Asp175) antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal antibody to Caspase 3 (cleaved Asp175)Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ＇216-Asp-\|-Gly-217＇ bond. Cleaves ａnd activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain ａnd the membrane attachment domain. Cleaves ａnd activates caspase-6, -7 ａnd -9. Involved in the cleavage of huntingtin. Hide
Immunogen	The antiserum was produced against synthesized peptide derived from human Caspase 3.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAIHCIHC-P
	IHC: 1:50~1:100 :
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Synonyms	ICE3 CPP-32 Apopain precursor SCA1 Yama protein Caspase-3 SREBP cleavage activity1 CASP3 Cysteine protease CPP32 Caspase3 SREBP cleavage activity 1 Caspase 3 CASP-3 SCA-1 CPP32 SCA 1 CPP 32 CASP 3 Caspase 3 (cleaved D175) Caspase 3 (clea Hide
Target	Caspase 3
Molecular Weight(MW)	20 ａnd 35 kDa (note)
Tissue Specificity	Caspase 3 (Cleaved-Asp175) Antibody detects endogenous levels of fragment of activated Caspase 3 resulting from cleavage adjacent to Asp175.

Application

Application

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Caspase 3 (Cleaved-Asp175) Antibody. The picture on the right is treated with the synthesized peptide.

Application Notes	IHC: 1:50~1:100 :

Additional Information

Form	Liquid
Storage Instructions	Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer	Phosphate buffered saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

关键词：稳定性强特异性强灵敏度高

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