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Product Name | Nrf2 Antibody Phospho (pS40) |
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Antibody Type | Primary Antibodies |
Clonality | Monoclonal |
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Isotype | Cocktail |
Clone Number | EP1809Y |
Host Species | Rabbit |
Tested Applications | IHCWB |
WB~~1:1000~10000 IHC~~1:100~250: | |
Species Reactivity | HumanMouseRat |
Concentration | 1 mg/ml |
Purification | Affinity purified |
Gene Synonyms | |
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Alternative Names | More |
Molecular Weight(MW) | 67827 Da |
Function | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region Hide |
Tissue Specificity | Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle |
Cellular Localization | Cylasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents |
Entrez Gene | 4780 |
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A. Western blot analysis on A) untreated and B) AP treated HepG2 cell lysates using anti-Phospho-Nrf2 (pS40) RabMAb 1:20,00 dilution.
B. Immunohistochemical analysis of paraffin-em
Application Notes | WB~~1:1000~10000 IHC~~1:100~250: |
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Form | Liquid |
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Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
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