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Product Name | Phospho-NFE2L2-pS40 Antibody |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | Ig |
Host Species | Rabbit |
Tested Applications | DB |
DB~~1:500: | |
Species Reactivity | Human |
Concentration | 1 mg/ml |
Purification |
Gene Synonyms | |
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Alternative Names | Hide |
Molecular Weight(MW) | 67827 Da |
Function | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region Hide |
Tissue Specificity | Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle |
Cellular Localization | Cylasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents |
Entrez Gene | 4780 |
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Nucleotide Accession | NP_006155 |
Dot blot analysis of anti-Phospho-NFE2L2-pS40 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Application Notes | DB~~1:500: |
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Form | Liquid |
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Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification. |
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