标题CD31 [SU03-59] Catalog Number：OM637243

提供者：上海笃玛生物科技有限公司发布时间：2024/8/20 阅读次数：12次 >>进入该公司展台

Product Name	CD31 [SU03-59]
Antibody Type	Primary Antibodies
Product description	Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth ａnd are thought to play an important role in embryogenesis ａnd development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms’ tumors, Ewing’s sarcomas ａnd some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily ａnd recognizes the β2/α1 ａnd β2/αM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets ａnd a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) ａnd lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM)-like protein ａnd is deleted in 66% of patients with Kallmann’s syndrome, anosmia with secondary hypogonadism. More
Immunogen	recombinant protein

Alternative Names	Adhesion molecule antibody CD31 antibody CD31 antigen antibody CD31 EndoCAM antibody EndoCAM antibody FLJ34100 antibody FLJ58394 antibody GPIIA antibody GPIIA＇ antibody PECA1 antibody PECA1_HUMAN antibody Pecam 1 antibody PECAM 1 CD31 EndoCAM antibody PECAM antibody PECAM-1 antibody Pecam1 antibody Platelet ａnd endothelial cell adhesion molecule 1 antibody Platelet endothelial cell adhesion molecule antibody Platelet/endothelial cell adhesion molecule 1 antibody More
Molecular Weight(MW)	82kDa(Observed: 130 kDa)
Cellular Localization	Cell junction. Cell membrane. Membrane.

SwissProt ID	P16284

Application

Fig1: Western blot analysis of CD31 on THP-1 cell lysates using anti-CD31 antibody at 1/1,000 dilution.
Application

Fig2: Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD31 antibody. Counter stained with hematoxylin.
Application

Fig3: Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD31 antibody. Counter stained with hematoxylin.
Application

Fig4: Immunohistochemical analysis of paraffin-embedded human uterus tissue using anti-CD31 antibody. Counter stained with hematoxylin.
Application

Fig5: Flow cytometric analysis of THP-1 cells with CD31 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.

Positive Control	THP-1, human tonsil tissue, human kidney tissue, human uterus tissue.
Application Notes	WB:1:1,000-1:2,000 IHC:1:50-1:200: FC:1:50-1:100

Form	Liquid
Storage Instructions	Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

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