标题CD31 Antibody Catalog Number：OM274439

CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1), is a type I integral membrane glycoprotein ａnd a member of the immunoglobulin superfamily of cell surface receptors.It is constitutively expressed on the surface of endothelial cells, ａnd concentrated at the junction between them. The antibody reacts with the murine form of the Platelet-Endothelial Cell Adhesion Molecule. The reactivity of the antibody is restricted to the isoform of the molecule that is selectively expressed by endothelial cells.The antigen is predominantly present at the lateral borders of endothelial cells as described for human PECAM-1.It is also weakly expressed on many peripheral lymphoid cells ａnd platelets.CD31 has been used to measure angiogenesis in association with tumor recurrence. Other studies have also indicated that CD31 ａnd CD34 can be used as markers for myeloid progenitor cells ａnd recognize different subsets of myeloid leukemia infiltrates (granular sarcomas).1) Mayr U et al. Circ Res 98:412-20 (2006).
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Ni-NTA purified recombinant CD31 expressed in E. Coli strain BL21 (DE3).

ELISAIHCWB

Human