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| Product Name | TGF beta1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 4F9C10,1B11B7 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHCWB |
| WB~~1:500 - 2000.: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | |
|---|---|
| Alternative Names | More |
| Molecular Weight(MW) | 44341 Da |
| Function | Multifunctional protein that controls proliferation, differentiation ａnd other functions in many cell types. Many cells synthesize TGFB1 ａnd have specific receptors for it. It positively ａnd negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation ａnd differentiation in committed osteoblasts More |
| Tissue Specificity | Highly expressed in bone. Abundantly expressed in articular cartilage ａnd chondrocytes ａnd is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage |
| Cellular Localization | Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 7040 |
|---|---|
| Nucleotide Accession | NP_000651.3 |
Figure 1: Western blot analysis using anti-TGF beta1 monoclonal antiobdy against truncated TGF beta1 recombinant protein.
| Application Notes | WB~~1:500 - 2000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of TGFbeta1 expressed in E. Coli. |
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