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您的位置：首页 > 技术文献 > 产品说明 > PI3K p85/p55 (phospho Tyr467/199) antibody Catalog Number：OM268505

标题PI3K p85/p55 (phospho Tyr467/199) antibody Catalog Number：OM268505

提供者：上海笃玛生物科技有限公司发布时间：2024/8/22 阅读次数：20次 >>进入该公司展台

Product Profile

Product Name	PI3K p85/p55 (phospho Tyr467/199) antibody
Antibody Type	Primary Antibodies
Product description	Rabbit Polyclonal antibody to PI3K P85 (Phospho Tyr467)Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake ａnd glycogen synthesis in insulin-sensitive tissues. Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain ａnd regulates their kinase activity. During insulin stimulation, it also binds to IRS-1./Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. More
Immunogen	Peptide sequence around phosphorylation site of tyrosine 467 (L-Y(p)-E-E-Y) derived from Human PI3K P85.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	WB
	Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity	HumanMouseRat
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Target Information

Gene Synonyms	GRB1 p85 p85-ALPHA PIK3R1 phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha phosphatidylinositol 3-kinase regulatory subunit polypeptide 1 (p85 alpha) PI3K regulatory subunit alpha ptdIns-3-kinase regulatory subunit alpha phosphatidyl More
Target	PI3K P85 (Phospho Tyr467)
Molecular Weight(MW)	85 (note)

Application

Application

Western blot analysis of extracts from 293 cells untreated or treated with sorbitol using PI3K P85 (phospho-Tyr467) Antibody .

Application Notes	Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	saline (without Mg2+ ａnd Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.

关键词：稳定性强特异性强灵敏度高

上一篇：Anti-PI3K p85 alpha antibody Catalog Number：OM641711 下一篇：DELTA TAU轴模块PMAC 602240-101

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