标题PI3 kinase p85 alpha antibody Catalog Number：OM268484

提供者：上海笃玛生物科技有限公司发布时间：2024/8/22 阅读次数：10次 >>进入该公司展台

Product Name	PI3 kinase p85 alpha antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal to PI3 kinase p85 alphaBinds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, ａnd acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake ａnd glycogen synthesis in insulin-sensitive tissues. More
Immunogen	KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y580 of human PIK3R1.

Gene Synonyms	Phosphatidylinositol 3-kinase regulatory subunit alpha PtdIns-3-kinase p85-alpha PIK3R1 GRB1 Phosphatidylinositol3kinase regulatory subunit alpha PI3-kinase p85-subunit alpha PI3K PI3kinase p85subunit alpha PtdIns3kinase p85alpha Phosphatidylinosi More
Target	PIK3R1
Molecular Weight(MW)	83.598 kDa (note)

Application

Formalin-fixed ａnd paraffin-embedded human skeletal muscle tissue reacted with PIK3R1-pY580 , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application

Western blot analysis of PIK3R1 (arrow) using rabbit polyclonal PIK3R1 Antibody (Y580) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PIK3R1 gene (Lane 2).

Application Notes	ELISA: Use at 1:1,000:

Form	Liquid
Storage Instructions	Store at at 2-8°C for up to 6 months. For long term storage, aliquot ａnd store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer	PBS with 0.09% (W/V) sodium azide

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