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您的位置:首页 > 技术文献 > 产品说明 > BRCA1 Antibody Catalog Number:OM272683

标题BRCA1 Antibody Catalog Number:OM272683

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/8/23   阅读次数:15次 >>进入该公司展台
 

Product Profile

Product Name BRCA1 Antibody
Antibody Type Primary Antibodies
Product description
Associated with several familial cancers, including breast cancer, ovarian cancer, and prostate cancer. The cumulative lifetime risk of breast cancer for women who carry mutations in BRCA1 is approximately 92%, while the cumulative lifetime risk for noncarriers is estimated to be 10%. BRCA1 and BRCA2 participate together in a pathway (or pathways) associated with the activation of double-strand break repair and/or homologous recombination.
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Immunogen
BRCA1 antibody was raised against amino acids surrounding Serine 1423 of BRCA1 (Human).

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

IHC

 
BRCA1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.:
Species Reactivity

Human

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol BRCA1
Alternative Names
BRCA1
BROVCA1
BRCC1
Breast cancer 1
early onset
PPP1R53
PSCP
PNCA4
RING finger protein 53
RNF53
BRCAI
Breast cancer 1 early onset
IRIS
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Tissue Specificity pSer1423

Database Links

Entrez Gene 672
Protein Accession P38398

Application

  • Application

    Immunohistochemistry staining of BRCA1 in breast tissue using BRCA1 Antibody.

Application Notes
BRCA1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.:

Additional Information

Form Liquid
Storage Instructions BRCA1 antibody should be stored long term (months) at -80 ˚C and short term (days) at -20 ˚C. As with all antibodies avoid freeze/thaw cycles.
Storage Buffer PBS, 0.02% sodium azide, 50% glycerol.

关键词:稳定性强  特异性强    灵敏度高  

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