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您的位置:首页 > 技术文献 > 产品说明 > BRCA1 antibody Catalog Number:OM241908

标题BRCA1 antibody Catalog Number:OM241908

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/8/23   阅读次数:13次 >>进入该公司展台
 

Product Profile

Product Name BRCA1 antibody
Antibody Type Primary Antibodies
Product description
Mouse polyclonal antiserum to BRCA1BRCA1, a 220kDa nuclear phosphoprotein, is recognized by this antibody. Mutations in the BRCA1 tumor suppressor gene greatly increase the risk of breast cancer. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cylasm. Recent studies suggest BRCA1 also has a role in DNA double strand break repair because of its association with Rad51.
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Immunogen
A synthetic peptide from the human BRCA1 protein corresponding to carboxyl terminal amino acids 1848-1863 (QELDTYLIPQIPHSHY).

Key Feature

Clonality Monoclonal
Isotype IgG
Host Species Mouse
Tested Applications

IHCIPWB

 
For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Predicted molecular weight: 208 kDa. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity

Human

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Synonyms
113705
RNF53
BRCA1
BRCAI
672
PSCP
BRCC1
P38398
IRIS
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Target BRCA1
Cellular Localization Nuclear

Application

  • Application

     

Positive Control HBL100
Application Notes
For IP: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Predicted molecular weight: 208 kDa. Optimal dilutions/concentrations should be determined by the researcher.:

Additional Information

Form Liquid
Storage Instructions Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Storage Buffer Anti-serum.

关键词:稳定性强  特异性强    灵敏度高  

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