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您的位置:首页 > 技术文献 > 产品说明 > FLT3 antibody Catalog Number:OM253327

标题FLT3 antibody Catalog Number:OM253327

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/8/26   阅读次数:14次 >>进入该公司展台
  

Product Profile

Product Name FLT3 antibody
Antibody Type Primary Antibodies
Product description
Rabbit Polyclonal antibody to FLT3This gene encodes a class III receptor tyrosine kinase that regulates hemaoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to auhosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cylasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hemaoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
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Immunogen
FLT3 antibody was raised against an 18 amino acid synthetic peptide near the center of human FLT3.

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAICC/IFWB

 
WB: 1 - 2 ug/ml. IF: 20 ug/ml:
Species Reactivity

HumanMouse

Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified

Target Information

Gene Synonyms
fms-related tyrosine kinase 3
FLK2
FLK-2
STK1
CD135
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Target FLT3
Tissue Specificity At least three isoforms of FLT3 are known to exist; this antibody will detect all isoforms.

Application

  • Application

    Immunofluorescence of FLT3 in human kidney tissue with FLT3 antibody at 20 ug/mL.

  • Application

    Western blot analysis of FLT3 in 3T3 cell lysate with FLT3 antibody at (A) 1 and (B)2 ug/mL.

Application Notes
WB: 1 - 2 ug/ml. IF: 20 ug/ml:

Additional Information

Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer PBS containing 0.02% sodium azide.

关键词:稳定性强  特异性强    灵敏度高  

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