标题FLT3 (phospho Tyr591) antibody Catalog Number：OM253324

提供者：上海笃玛生物科技有限公司发布时间：2024/8/26 阅读次数：15次 >>进入该公司展台

Product Profile

Product Name	FLT3 (phospho Tyr591) antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal antibody to FLT3 (phospho Y591)This gene encodes a class III receptor tyrosine kinase that regulates hemaoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, ａnd a cylasmic kinase domain split into two parts by a kinase-ｉnsert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to auhosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates ａnd activates multiple cylasmic effector molecules in pathways involved in apoptosis, proliferation, ａnd differentiation of hemaoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia ａnd acute lymphoblastic leukemia. [provided by RefSeq] More

Product Name

FLT3 (phospho Tyr591) antibody

Antibody Type

Primary Antibodies

Product description

Rabbit polyclonal antibody to FLT3 (phospho Y591)This gene encodes a class III receptor tyrosine kinase that regulates hemaoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, ａnd a cylasmic kinase domain split into two parts by a kinase-ｉnsert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to auhosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates ａnd activates multiple cylasmic effector molecules in pathways involved in apoptosis, proliferation, ａnd differentiation of hemaoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia ａnd acute lymphoblastic leukemia. [provided by RefSeq]
More

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ELISAIHCIHC-PWB
	Suggested starting dilutions are as follows. WB: 1:500-1:1000,IHC: 1:50-1:100,ELISA: 1:4000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity	Human
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification	Affinity purified

Target Information

Gene Synonyms	CD135 FLK2 STK1
Target	FLT3 (phospho Y591)

Application

Application

Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue using FLT3 (Phospho-Tyr591) Antibody

Application Notes	Suggested starting dilutions are as follows. WB: 1:500-1:1000,IHC: 1:50-1:100,ELISA: 1:4000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	PBS (without Mg2+and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide ａnd 50% glycerol.

关键词：稳定性强特异性强灵敏度高

上一篇：FLT3 antibody Catalog Number：OM253327 下一篇：FLT3 (Tyr589/591) Antibody Catalog Number：OM233328

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标题FLT3 (phospho Tyr591) antibody Catalog Number：OM253324

Product Profile

Key Feature

Target Information

Application

Application

Additional Information

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