标题FGF4 antibody Catalog Number：OM252983

提供者：上海笃玛生物科技有限公司发布时间：2024/8/27 阅读次数：16次 >>进入该公司展台

Product Profile

Product Name	FGF4 antibody
Antibody Type	Primary Antibodies
Product description	Rabbit polyclonal antibody to FGF4Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic ａnd cell survival activities ａnd play key roles in growth ａnd survival of stem cells during embryogenesis, tissue regeneration, ａnd carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity ａnd is a potent angiogenic factor, expressed in several highly vascularized tumors ａnd also in adult mouse testis, intestine, ａnd brain. Studies on the mouse homolog suggests a function in bone morphogenesis ａnd limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation ａnd neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells ａnd a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development. More

Product Name

FGF4 antibody

Antibody Type

Primary Antibodies

Product description

Rabbit polyclonal antibody to FGF4Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic ａnd cell survival activities ａnd play key roles in growth ａnd survival of stem cells during embryogenesis, tissue regeneration, ａnd carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity ａnd is a potent angiogenic factor, expressed in several highly vascularized tumors ａnd also in adult mouse testis, intestine, ａnd brain. Studies on the mouse homolog suggests a function in bone morphogenesis ａnd limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation ａnd neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells ａnd a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.
More

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAICC/IFWB
	ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	HumanMouse
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Synonyms	Fibroblast growth factor 4 HBGF-4 FGF4 Heparin secretorytransforming protein Fibroblast growth factor4 HST1 HST Transforming protein KS3 HBGF4 Kaposi sarcoma oncogene HST-1 Heparin secretory-transforming protein HST 1 HBGF 4 More
Target	FGF4
Tissue Specificity	This antibody is specific for FGF4

Application

Application

Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.
Application

Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 ａnd (B) 1 ug/ml.
Application

Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/ml.

Positive Control	Blocking Peptide: Cat.No. GTX85040-PEP - FGF4 Peptide Lysates: Cat. No. GTX27901 - 3T3 (NIH) Cell Lysate
Application Notes	ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Keep as concentrated solution. Aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer	Antibody is supplied in PBS containing 0.02% sodium azide

关键词：稳定性强特异性强灵敏度高

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标题FGF4 antibody Catalog Number：OM252983

Product Profile

Key Feature

Target Information

Application

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Additional Information

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