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| Product Name | Rabbit anti-CD33 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | BovineHuman |
| Concentration | 1 mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CD33 |
|---|---|
| Gene Synonyms | Hide |
| Gene Full Name | CD33 molecule |
| Gene Summary | CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cylasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro). Hide |
| Alternative Names | Hide |
| Molecular Weight(MW) | 38kDa |
| Sequence | 364 amino acids |
| Entrez Gene | 945 |
|---|---|
| SwissProt ID | P20138 |
| Protein Accession | NP_001763 |
Titration: 1.0 ug/ml
Positive Control: Fetal Heart
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot ａnd store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol. |
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