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Product Name | Anti-WHSC2 antibody |
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Antibody Type | Primary Antibodies |
Immunogen | Polypeptide |
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | ELISAIHCWB |
WB:1:200-1:2000 IHC:1:200-1:2000 | |
Species Reactivity | HumanMouseRat |
Concentration | 1mg/ml |
Purification | Protein A |
Gene Symbol | NELFA |
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Gene Synonyms | |
Gene Full Name | negative elongation factor complex member A |
Gene Summary | This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008] More |
Molecular Weight(MW) | 57KD |
Cellular Localization | Nucleus |
Western blot analysis using WHSC2 antibody against A549(1) cell lysate.
Immunohistochemical analysis of paraffin-em
Immunohistochemical analysis of paraffin-em
Application Notes | WB:1:200-1:2000 IHC:1:200-1:2000 |
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Form | Liquid |
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Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
关键词:Product Profile Product NameAnti-WHSC2 antibody Antibody TypePrimary Antibodies Immunogen Polype
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