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您的位置:首页 > 技术文献 > 产品说明 > WHSC2 Antibody (Center) Catalog Number:OM224700

标题WHSC2 Antibody (Center) Catalog Number:OM224700

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/2   阅读次数:6次 >>进入该公司展台
 

Product Profile

Product Name WHSC2 Antibody (Center)
Antibody Type Primary Antibodies

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

WB

 
WB~~1:100~500:
Species Reactivity

Human

Concentration 1 mg/ml
Purification  

Target Information

Gene Synonyms
WHSC2
Alternative Names
WHSC2
NELFA
Negative elongation factor A
Wolf-Hirschhorn syndrome candidate 2 protein
More 
Molecular Weight(MW) 57277 Da
Function
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex
More 
Tissue Specificity Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney
Cellular Localization Nucleus.

Database Links

Entrez Gene 7469
Nucleotide Accession NP_005654.3

Application

  • Application

    WHSC2 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the WHSC2 antibody detected the WHSC2 protein (arrow).

Application Notes
WB~~1:100~500:

Additional Information

Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

关键词:稳定性强  特异性强    灵敏度高  

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