标题Guanylyl Cyclase alpha 1 Antibody Catalog Number：OM280530

提供者：上海笃玛生物科技有限公司发布时间：2024/9/2 阅读次数：13次 >>进入该公司展台

Product Name	Guanylyl Cyclase alpha 1 Antibody
Antibody Type	Primary Antibodies
Product description	Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha ａnd a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP ａnd functions as the main receptor for nitric oxide ａnd nitrovasodilator drugs.1) Saino, M., et al., Oncol. Rep. 12(1):47-52 (2004).
Immunogen	This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3).

Clonality	Polyclonal
Isotype	Ig
Host Species	Rabbit
Tested Applications	IHC-PWB
	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:
Species Reactivity	Human
Concentration	1 mg/ml

Gene Symbol	GUCY1A3
Alternative Names	Guanylate cyclase soluble subunit alpha-3 GCS-alpha-3 GCS-alpha-1 Soluble guanylate cyclase large subunit GUCY1A3 GUC1A3 GUCSA3 GUCY1A1 More
Molecular Weight(MW)	77 kDa

Entrez Gene	2982
Protein Accession	Q02108

Application

Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane).
Application

Formalin-fixed ａnd paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.
Application

Western blot analysis of GUCY1A3 using GUCY1A3 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2).

Application Notes	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100:

Form	Liquid
Storage Instructions	Store at 4˚C for three months ａnd -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.

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