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| Product Name | Anti-PDE1B antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:2000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PDE1B |
|---|---|
| Gene Synonyms | |
| Gene Full Name | phosphodiesterase 1B |
| Gene Summary | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, ａnd PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP ａnd cGMP, with a preference for cGMP as a substrate. cAMP ａnd cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] More |
| Molecular Weight(MW) | 63KD |
| Cellular Localization | Cylasm |
Western blot analysis using PDE1B antibody against K562(1) cell lysate.
Immunohistochemical analysis of paraffin-em
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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