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您的位置：首页 > 技术文献 > 产品说明 > DKK3 [C6-A5] Catalog Number：OM627641

标题DKK3 [C6-A5] Catalog Number：OM627641

提供者：上海笃玛生物科技有限公司发布时间：2024/9/4 阅读次数：11次 >>进入该公司展台

Product Profile

Product Name	DKK3 [C6-A5]
Antibody Type	Primary Antibodies
Product description	Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt ａnd by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis ａnd eye formation. In the adult, Dkks are implicated in bone formation ａnd bone disease, cancer ａnd Alzheimer disease. More
Immunogen	Recombinant protein

Key Feature

Clonality	Monoclonal
Isotype	IgG1
Host Species	Mouse
Tested Applications	WBIHC
	WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity	Human
Concentration	2 mg/mL.

Target Information

Alternative Names	Dickkopf 3 antibody Dickkopf 3 homolog (Xenopus laevis) antibody Dickkopf 3 homolog antibody Dickkopf homolog 3 antibody Dickkopf related protein 3 antibody Dickkopf related protein 3 Precursor antibody Dickkopf WNT signaling pathway inhibitor 3 antibody Dickkopf Xenopus homolog of 3 antibody Dickkopf-3 antibody Dickkopf-related protein 3 antibody Dickkopf3 antibody DKK 3 antibody Dkk-3 antibody DKK3 antibody DKK3_HUMAN antibody hDkk 3 antibody hDkk-3 antibody hDkk3 antibody Regulated in glioma antibody REIC antibody RIG antibody RIG-like 5-6 antibody RIG-like 7-1 antibody More
Molecular Weight(MW)	38 kDa
Cellular Localization	Secreted.

Database Links

SwissProt ID	Q9UBP4

Application

Application

Fig1: Western blot analysis of DKK3 on human DKK3 recombinant protein using anti-DKK3 antibody at 1/1,000 dilution.
Application

Fig2: Western blot analysis of DKK3 on HEK293 (1) ａnd DKK3-hIgGFc transfected HEK293 (2) cell lysate using anti-DKK3 antibody at 1/1,000 dilution.
Application

Fig3: Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-DKK3 antibody. Counter stained with hematoxylin.

Positive Control	Human DKK3 recombinant protein, DKK3-hIgGFc transfected HEK293 cell lysate, human brain tissue.
Application Notes	WB:1:250~1:1000 IHC:1:20~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form	Liquid
Storage Instructions	Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer	1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

关键词：稳定性强特异性强灵敏度高

上一篇：Anti-DKK3 antibody Catalog Number：OM642652 下一篇：DKK3 antibody Catalog Number：OM250118

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