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| Product Name | CD55 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 561CT4.2.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB~~1:100: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
| Gene Synonyms | |
|---|---|
| Alternative Names | More |
| Molecular Weight(MW) | 41400 Da |
| Function | This protein recognizes C4b ａnd C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b ａnd C3b are locally generated during C4 ａnd c3 activation Interaction of daf with cell-associated C4b ａnd C3b polypeptides interferes with their ability to catalyze the conversion of C2 ａnd factor B to enzymatically active C2a ａnd Bb ａnd thereby prevents the formation of C4b2a ａnd C3bBb, the amplification convertases of the complement cascade More |
| Tissue Specificity | Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, ａnd variants of the molecule are present in body fluids ａnd in extracellular matrix |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 1604 |
|---|---|
| Nucleotide Accession | NP_001108224.1 |
CD55 Antibody(Cat. #AM2092b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CD55 antibody detected the CD55 protein (arrow).
| Application Notes | WB~~1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high ａnd low pH buffers ａnd neutralized immediately, followed by dialysis against PBS. |
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