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您的位置：首页 > 技术文献 > 产品说明 > DAF Antibody Catalog Number：OM276710

标题DAF Antibody Catalog Number：OM276710

提供者：上海笃玛生物科技有限公司发布时间：2024/9/5 阅读次数：14次 >>进入该公司展台

Product Profile

Product Name	DAF Antibody
Antibody Type	Primary Antibodies
Product description	The decay-accelerating factor (DAF), also known as CD55, is an integral membrane glycoprotein that is involved in the regulation of the complement cascade (1). DAF limits excessive complement activation by accelerating their decay following DAF binding, thereby disrupting the cascade ａnd preventing damage to host cells (2). Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM) (3).1) Nicholson-Weller A, March JP, Rosen CE, et al. Surface membrane expression by human blood leukocytes ａnd platelts of decay-accelerating factor, a regulatory protein of the complement system. Blood 1985; 65:1237-44. More
Immunogen	DAF antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DAF. The immunogen is located within amino acids 360 - 410 of DAF.

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	ELISAIFIHC-PWB
	DAF body can be used for detection of DAF by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	CD55
Alternative Names	Decay-accelerating factor CD55 molecule decay accelerating factor for complement (Cromer blood group) CD55 CR TC CROM More
Molecular Weight(MW)	Predicted: 48 kDa Observed: 49 kDa
Sequence Similarities	2) Cat. No. 10-101 - Human Lung Tissue Slide
Tissue Specificity	DAF antibody is human specific. At least two isoforms of DAF are known to exist; this antibody will only detect the longest isoform.

Database Links

Entrez Gene	1604
Protein Accession	NP_001108224

Application

Application

Western blot analysis of DAF in A549 cell lysate with DAF antibody at 1 μg/ml.
Application

Immunofluorescence of DAF in human lung tissue with DAF antibody at 20 μg/ml.
Application

Immunohistochemistry of DAF in human lung tissue with DAF antibody at 5 μg/ml.

Positive Control	1) Cat. No. 1203 - A549 Cell Lysate
Application Notes	DAF body can be used for detection of DAF by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.:

Additional Information

Form	Liquid
Storage Instructions	DAF antibody can be stored at 4˚C for three months ａnd -20˚C, stable for up to one year.
Storage Buffer	DAF antibody is supplied in PBS containing 0.02% sodium azide.

关键词：稳定性强特异性强灵敏度高

上一篇：CD55 Catalog Number：OM640768 下一篇：CD55 Antibody (N-term) Catalog Number：OM229252

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