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您的位置：首页 > 技术文献 > 产品说明 > SPIB Catalog Number：OM630867

标题SPIB Catalog Number：OM630867

提供者：上海笃玛生物科技有限公司发布时间：2024/9/9 阅读次数：19次 >>进入该公司展台

Product Profile

Product Name	SPIB
Antibody Type	Primary Antibodies
Product description	Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5＇-GAGGAA-3＇) that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon ａnd block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development ａnd antigenic stimulation. More
Immunogen	KLH conjugated synthetic peptide derived from human SPIB 181-262/262

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	WB:1:500-2000:
Species Reactivity	HumanMouseRatCowHorseRabbitSheep
Concentration	1 mg/mL.

Target Information

Alternative Names	SPI B Spi B transcription factor Spib SPIB_HUMAN Transcription factor Spi-B.
Molecular Weight(MW)	29 KDa
Cellular Localization	Cylasm ａnd Nucleus.

Database Links

SwissProt ID	Q01892

Application

Application

Fig1: Sample: Lymph node (Mouse) Lysate at 40 ug Primary: Anti-SPIB (ER1917-11) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 29 kD
Application

Fig2: Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-SPIB (ER1917-11) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 29 kD

Positive Control	Expressed in plasmacytoid dendritic cells (pDCs) ａnd B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver.
Application Notes	WB:1:500-2000:

Additional Information

Form	Liquid
Storage Instructions	Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 ａnd 50% Glycerol.

关键词：稳定性强特异性强灵敏度高

上一篇：SPIB Catalog Number：OM640801 下一篇：SPIB Antibody Catalog Number：OM292065

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