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您的位置：首页 > 技术文献 > 产品说明 > SPIB Antibody Catalog Number：OM292065

标题SPIB Antibody Catalog Number：OM292065

提供者：上海笃玛生物科技有限公司发布时间：2024/9/9 阅读次数：21次 >>进入该公司展台

Product Profile

Product Name	SPIB Antibody
Antibody Type	Primary Antibodies
Product description	SPIB is a member of the ETS transcription factor family that influences lymphoid development ａnd activity ａnd binds the consensus DNA site GGA (A/T) through a unique winged helix-turn-helix motif known as the ETS domain (1). SPIB is found in hemaoietic cells such as B cells ａnd plasmacytoid dendritic cells (DC) (2,3). It promotes the development of plasmacytoid dendritic cells (pDCs) or natural interferon (IFN)-producing cells. SPIB may be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development ａnd antigenic stimulation (3,4).1) Ray D, Bosselut R, Ghysdael J, et al. Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1. Mol. Cell Biol. 1992; 12:4297-304. More
Immunogen	SPIB antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SPIB. The immunogen is located within amino acids 200 - 250 of SPIB.

Key Feature

Clonality	Polyclonal
Isotype	IgG
Host Species	Rabbit
Tested Applications	WB
	SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.:
Species Reactivity	Human
Concentration	1 mg/ml
Purification	Affinity purified

Target Information

Gene Symbol	SPIB
Alternative Names	Spi-B transcription factor SPI-B
Molecular Weight(MW)	Predicted: 19, 25, 29 kDa Observed: 20 kDa
Sequence Similarities	Predicted species reactivity based on immunogen sequence: Pig: (88%)
Tissue Specificity	SPIB antibody is human, mouse ａnd rat reactive. At least four isoforms of SPIB are known to exist; this antibody will detect all but isoform 3.

Database Links

Entrez Gene	6689
Protein Accession	NP_003112

Application

Application

Immunohistochemistry of SPIB in human prostate tissue with SPIB antibody at 2.5 μg/mL.
Application

Immunohistochemistry of SPIB in human prostate tissue with SPIB antibody at 2.5 μg/ml.
Application

Western blot analysis of SPIB in human prostate tissue lysate with SPIB antibody at 1 μg/ml.

Positive Control	1) Cat. No. 1312 - Human Prostate Tissue Lysate
Application Notes	SPIB antibody can be used for detection of SPIB by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.:

Additional Information

Form	Liquid
Storage Instructions	SPIB antibody can be stored at 4˚C for three months ａnd -20˚C, stable for up to one year.
Storage Buffer	SPIB antibody is supplied in PBS containing 0.02% sodium azide.

关键词：稳定性强特异性强灵敏度高

上一篇：SPIB Catalog Number：OM630867 下一篇：SPIB Antibody Catalog Number：OM292064

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