标题INCENP antibody Catalog Number：OM259341

提供者：上海笃玛生物科技有限公司发布时间：2024/9/10 阅读次数：14次 >>进入该公司展台

Product Name	INCENP antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [3D2] to INCENPIn mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins ａnd ＇passenger,＇ or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), ａnd CENPD (MIM 117142). The term ＇passenger proteins＇ encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw ａnd Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cylasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); ａnd CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw ａnd Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle pro More
Immunogen	The immunogen corresponding to a region within amino acids 369 ａnd 583 of human INCENP expressed in E. Coli.

Clonality	Monoclonal
Isotype	IgG1
Clone Number	3D2
Host Species	Mouse
Tested Applications	ELISAFACSICC/IFIHCIHC-PWB
	ELISA: 1/10000.:
Species Reactivity	Human
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification

Target	INCENP
Molecular Weight(MW)	105.4 kDa (note)

Application

ELISA analysis of control antigen ａnd antigen using INCENP antibody [3D2].
Application

FACS analysis of Jurkat cells using INCENP antibody [3D2] (green) or a negative control (red).
Application

ICC/IF analysis of HepG2 cells using INCENP antibody [3D2] (green) ａnd DRAQ5 fluorescent DNA dye (blue).
Application

IHC-P analysis of cervical cancer tissues using INCENP antibody [3D2].
Application

IHC-P analysis of rectum cancer tissues using INCENP antibody [3D2].
Application

WB analysis of lysates from (1) untransfected ａnd (2) INCENP (a.a. 369-583)-hIgGFc transfected HEK293 cells using INCENP antibody [3D2].
Application

WB analysis of human INCENP recombinant protein using INCENP antibody [3D2].

Application Notes	ELISA: 1/10000.:

Form	Liquid
Storage Instructions	4°C; -20°C for long term storage
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide ａnd 0.5% protein stabilizer.

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