标题GluR2 Antibody Catalog Number：OM279910

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) ａnd they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann ａnd Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003)1) Chung HJ, Steinberg JP, Huganir RL, Linden DJ (2003) Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science 300:1751-1755.
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Peptide corresponding to amino acid residues from rat GluR2, conjugated to keyhole limpet hemocyanin (KLH).

WB

Zebra Fish