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Product Name | Gab1 Mutant Y659 Antibody |
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Antibody Type | Primary Antibodies |
Clonality | Polyclonal |
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Isotype | Ig |
Host Species | Rabbit |
Tested Applications | IHCDB |
IHC~~1:50~100 DB~~1:100~500: | |
Species Reactivity | Human |
Concentration | 1 mg/ml |
Purification |
Alternative Names | More |
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Molecular Weight(MW) | 76616 Da |
Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR) |
Tissue Specificity | This Gab1 Mutant Y659 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids surrounding Y659 of human GAB1 Y659. |
Entrez Gene | 2549 |
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Dot blot analysis of anti-hGab1-Y659H mutant Pab on nitrocellulose membrane. 50ng of Mutant-peptide or Non Mutant-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
Application Notes | IHC~~1:50~100 DB~~1:100~500: |
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Form | Liquid |
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Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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