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| Product Name | Anti-RAP1A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCWB |
| WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | RAP1A |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | RAP1A, member of RAS oncogene family |
| Gene Summary | This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state ａnd activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), ａnd inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs ａnd GAPs. The encoded protein regulates signaling pathways that affect cell proliferation ａnd adhesion, ａnd may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 ａnd 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] More |
| Molecular Weight(MW) | 21KD |
| Cellular Localization | Cell junction, Cell membrane, Cylasm, Endosome, Membrane |
Western blot analysis using RAP1A antibody against Hek293(1) cell lysate.
Immunohistochemical analysis of paraffin-em
Immunofluorescence analysis of Hela cells using RAP1A antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | WB:1:200-1:2000 IHC:1:200-1:2000 ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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