标题ALPL antibody Catalog Number：OM239240

提供者：上海笃玛生物科技有限公司发布时间：2024/9/18 阅读次数：7次 >>进入该公司展台

Product Name	ALPL antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [2F4] to ALPLThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, ａnd liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue ａnd is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia ａnd includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset ａnd severity of symptoms. Alternatively spl More
Immunogen	The immunogen corresponding to human ALPL expressed in E. Coli.

Clonality	Monoclonal
Isotype	IgG1
Clone Number	2F4
Host Species	Mouse
Tested Applications	ELISAFACSIHCIHC-PWB
	ELISA: 1/10000.:
Species Reactivity	Human
Concentration	1 mg/ml (Please refer to the vial label for the specific concentration)
Purification

Gene Synonyms	TNSALP APTNAP HOPS TNAP AP-TNAP More
Target	ALPL
Molecular Weight(MW)	57.3 kDa (note)

Application

WB analysis of human ALPL (a.a. 18-502) recombinant protein using ALPL antibody [2F4].
Application

IHC-P analysis of ovarian cancer tissues using ALPL antibody [2F4].
Application

WB analysis of (1) HeLa ａnd (2) NTERA-2 lysates using ALPL antibody [2F4].
Application

FACS analysis of MCF-7 cells using ALPL antibody [2F4] (green) or a negative control (red).
Application

ELISA analysis of control antigen ａnd antigen using ALPL antibody [2F4].

Application Notes	ELISA: 1/10000.:

Form	Liquid
Storage Instructions	4°C; -20°C for long term storage
Storage Buffer	Purified antibody in PBS with 0.05% sodium azide ａnd 0.5% protein stabilizer.

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