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您的位置:首页 > 技术文献 > 产品说明 > ALPL antibody Catalog Number:OM239240

标题ALPL antibody Catalog Number:OM239240

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/18   阅读次数:22次 >>进入该公司展台
 

Product Profile

Product Name ALPL antibody
Antibody Type Primary Antibodies
Product description
Mouse Monoclonal Antibody [2F4] to ALPLThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spl
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Immunogen
The immunogen corresponding to human ALPL expressed in E. Coli.

Key Feature

Clonality Monoclonal
Isotype IgG1
Clone Number 2F4
Host Species Mouse
Tested Applications

ELISAFACSIHCIHC-PWB

 
ELISA: 1/10000.:
Species Reactivity

Human

Concentration 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification  

Target Information

Gene Synonyms
TNSALP
APTNAP
HOPS
TNAP
AP-TNAP
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Target ALPL
Molecular Weight(MW) 57.3 kDa (note)

Application

  • Application

    WB analysis of human ALPL (a.a. 18-502) recombinant protein using ALPL antibody [2F4].

  • Application

    IHC-P analysis of ovarian cancer tissues using ALPL antibody [2F4].

  • Application

    WB analysis of (1) HeLa and (2) NTERA-2 lysates using ALPL antibody [2F4].

  • Application

    FACS analysis of MCF-7 cells using ALPL antibody [2F4] (green) or a negative control (red).

  • Application

    ELISA analysis of control antigen and antigen using ALPL antibody [2F4].

Application Notes
ELISA: 1/10000.:

Additional Information

Form Liquid
Storage Instructions 4°C; -20°C for long term storage
Storage Buffer Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer.

关键词:稳定性强  特异性强    灵敏度高  

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