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您的位置:首页 > 技术文献 > 产品说明 > FGG Antibody Catalog Number:OM278839

标题FGG Antibody Catalog Number:OM278839

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/19   阅读次数:19次 >>进入该公司展台
 

Product Profile

Product Name FGG Antibody
Antibody Type Primary Antibodies
Product description
FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this protein lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia.1) Sie,M.P., Isaacs,A. J. Hypertens. 27 (7), 1392-1398 (2009)
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Immunogen
This FGG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from the C-terminal region of human FGG.

Key Feature

Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications

FACSIHC-PWB

 
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:
Species Reactivity

Human

Concentration 1 mg/ml

Target Information

Gene Symbol FGG
Alternative Names
Fibrinogen gamma chain
FGG
Molecular Weight(MW) 52 kDa

Database Links

Entrez Gene 2266
Protein Accession P02679

Application

  • Application

    Flow cytometric analysis of T47D cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

  • Application

    Western blot analysis in human blood plasma cell line lysates (35ug/lane).

  • Application

    FGG Antibody (RB18714) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Application Notes
For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50:

Additional Information

Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.

关键词:稳定性强  特异性强    灵敏度高  

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