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您的位置：首页 > 技术文献 > 产品说明 > FGG Antibody Catalog Number：OM278837

标题FGG Antibody Catalog Number：OM278837

提供者：上海笃玛生物科技有限公司发布时间：2024/9/19 阅读次数：14次 >>进入该公司展台

Product Profile

Product Name	FGG Antibody
Antibody Type	Primary Antibodies
Product description	FGG is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in its gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia.The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen ａnd fibrin regulate cell adhesion ａnd spreading, display vasoconstrictor ａnd chemotactic activities, ａnd are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia ａnd thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.1) Uitte (2006) J. Thromb. Haemost. 4 (2), 474-476. More
Immunogen	Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGG.

Key Feature

Clonality	Polyclonal
Host Species	Rabbit
Tested Applications	ELISAWB
	FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity	DogHumanMouseRat
Concentration	1 mg/ml
Purification	Protein A

Target Information

Gene Symbol	FGG
Alternative Names	FGG
Molecular Weight(MW)	46 kDa, 52 kDa

Database Links

Entrez Gene	2266
Protein Accession	NP_000500

Application

Application

Antibody used in WB on Human Liver at 2.5 ug/ml.

Positive Control	1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Application Notes	FGG antibody can be used for detection of FGG by ELISA at 1:312500. FGG antibody can be used for detection of FGG by western blot at 2.5 μg/mL, ａnd HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form	Liquid
Storage Instructions	For short periods of storage (days) store at 4˚C. For longer periods of storage, store FGG antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer	IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide ａnd 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt

关键词：稳定性强特异性强灵敏度高

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