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| Product Name | Anti-NEFL antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IF |
| ICC/IF:1:100-1:500 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NEFL |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | neurofilament light chain |
| Gene Summary | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, ａnd heavy chains. Neurofilaments comprise the axoskeleton ａnd they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons ａnd dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) ａnd 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008] More |
| Molecular Weight(MW) | 62KD |
| Cellular Localization | Cell projection, Cylasm, Cytoskeleton, Intermediate filament |
Immunofluorescence analysis of C2C12 cells using NEFL antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | ICC/IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
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