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您的位置:首页 > 技术文献 > 产品说明 > Neurofilament NF-L Antibody Catalog Number:OM286038

标题Neurofilament NF-L Antibody Catalog Number:OM286038

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/19   阅读次数:58次 >>进入该公司展台
 

Product Profile

Product Name Neurofilament NF-L Antibody
Antibody Type Primary Antibodies
Product description
Neurofilaments are the 10nm or intermediate filament proteins specifically in neurons, and are composed predominantly of three major proteins called NF- NF-M and NF-H. NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68 kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease.1) Harris, J., Ayyub, C. and Shaw G. (1991) A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H. J Neurosci Res 30:47-62.
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Immunogen
Preparation of porcine intermediate filaments.

Key Feature

Clonality Monoclonal
Isotype IgG1
Host Species Mouse
Tested Applications

IHCWB

 
IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity

BovineChickenHumanMouseRat

Concentration 1 mg/ml

Target Information

Gene Symbol NEFL
Alternative Names
NFL
NF-L
NF68
CMT1F
CMT2E
NFL
68 kDa neurofilament protein
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Molecular Weight(MW) 68
Tissue Specificity Specific for the ~68k Neurofilament L protein.

Database Links

Entrez Gene 4747
Protein Accession P07196

Application

  • Application

    Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.

Application Notes
IHC:1:50~1:200
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.

Additional Information

Form Liquid
Storage Instructions Neurofilament NF-L antibody can be stored at -20˚C and is stable at -20˚C for at least 1 year.
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
 

关键词:稳定性强  特异性强    灵敏度高  

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