标题DLK1 antibody Catalog Number：OM250156

提供者：上海笃玛生物科技有限公司发布时间：2024/9/23 阅读次数：5次 >>进入该公司展台

Product Name	DLK1 antibody
Antibody Type	Primary Antibodies
Product description	Mouse Monoclonal Antibody [3A10] to DLK1This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on ｃhr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal ａnd paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child ａnd adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy ａnd decreased fat mass. [provided by RefSeq, Mar 2010] More
Immunogen	The immunogen corresponding to human DLK1 expressed in E. Coli.

Gene Synonyms	DLK-1 DELTA1 ZOG PREF1 PG2 FA1 DLK PREF-1 More
Target	DLK1
Molecular Weight(MW)	41 kDa (note)

Application

ELISA analysis of control antigen ａnd antigen using DLK1 antibody [3A10].
Application

WB analysis of human DLK1 (a.a. 174-349) recombinant protein using DLK1 antibody [3A10].
Application

ICC/IF analysis of U251 cells using DLK1 antibody [3A10] (green), Alexa Fluor-555 phalloidin (red) ａnd DRAQ5 fluorescent DNA dye (blue).
Application

FACS analysis of NIH3T3 cells using DLK1 antibody [3A10] (green) or a negative control (red).