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| Product Name | Anti-NQO1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHCWB |
| WB:1:500-1:2000 IHC:1:200-1:1000 ICC:1:50-1:200 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NQO1 |
|---|---|
| Gene Synonyms | More |
| Gene Full Name | NAD(P)H qui dehydrogenase 1 |
| Gene Summary | This gene is a member of the NAD(P)H dehydrogenase (qui) family ａnd encodes a cylasmic 2-electron reductase. This FAD-binding protein forms homodimers ａnd reduces quis to hydroquis. This protein＇s enzymatic activity prevents the one electron reduction of quis that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, ａnd susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors ａnd is also associated with Alzheimer＇s disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] More |
| Molecular Weight(MW) | 31 kDa |
| Cellular Localization | Cylasm |
Figure 1: Western blot analysis using NQO1 antibody against T24(1) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-em
Figure 2: Immunofluorescence analysis of Nih3T3 cells using NQO1 antibody (green). Blue: DAPI fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
| Application Notes | WB:1:500-1:2000 IHC:1:200-1:1000 ICC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% PC300. |
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