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您的位置:首页 > 技术文献 > 产品说明 > PHB Antibody Catalog Number:OM287956

标题PHB Antibody Catalog Number:OM287956

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/26   阅读次数:10次 >>进入该公司展台
 

Product Profile

Product Name PHB Antibody
Antibody Type Primary Antibodies
Product description
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.1) Fraering, P.C., et al., (2004) Biochemistry 43 (30), 9774-9789.
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Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHB.

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

ELISAIHCWB

 
PHB antibody can be used for detection of PHB by ELISA at 1:1562500. PHB antibody can be used for detection of PHB by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Species Reactivity

HumanMouseRat

Concentration 1 mg/ml
Purification Affinity purified

Target Information

Gene Symbol PHB
Alternative Names
PHB
PHB1
HEL-215
HEL-S-54e
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Molecular Weight(MW) 30 kDa

Database Links

Entrez Gene 5245
Protein Accession NP_002625

Application

  • Application

    Antibody used in IHC on Human Stomach.

  • Application

    Antibody used in WB on Human Jurkat 0.2-1 ug/ml.

Positive Control 1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes
PHB antibody can be used for detection of PHB by ELISA at 1:1562500. PHB antibody can be used for detection of PHB by western blot at 1.0-2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:

Additional Information

Form Liquid
Storage Instructions For short periods of storage (days) store at 4˚C. For longer periods of storage, store PHB antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.

关键词:稳定性强  特异性强    灵敏度高  

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