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您的位置:首页 > 技术文献 > 产品说明 > Anti-MCM2 antibody Catalog Number:OM642613

标题Anti-MCM2 antibody Catalog Number:OM642613

   

提供者:上海笃玛生物科技有限公司    发布时间:2024/9/27   阅读次数:3次 >>进入该公司展台
 

Product Profile

Product Name Anti-MCM2 antibody
Antibody Type Primary Antibodies
Product description
Polypeptide

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

ELISAIHCWB

 
WB:1:200-1:2000
IHC:1:200-1:2000
Species Reactivity

HumanMouseRat

Concentration 1mg/ml
Purification Protein A

Target Information

Gene Symbol MCM2
Gene Synonyms
BM28
CCNL1
CDCL1
cdc19
DFNA70
D3S3194
MITOTIN
More 
Gene Full Name minichromosome maintenance complex component 2
Gene Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
More 
Molecular Weight(MW) 102kD(Observed:90 kD)
Cellular Localization Chromosome, Nucleus

Application

  • WB

    Western blot analysis using MCM2 antibody against Hela(1) cell lysate.

  • IHC

    Immunohistochemical analysis of paraffin-embedded lung cancer tissues using MCM2 antibody with DAB staining.

  • IHC

    Immunohistochemical analysis of paraffin-embedded colon cancer tissues tissues using MCM2 antibody with DAB staining.

Application Notes
WB:1:200-1:2000
IHC:1:200-1:2000

Additional Information

Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.

关键词:稳定性强  特异性强    灵敏度高  

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